Key result
Patient-specific computer simulation is presented as a potential solution to improve transcatheter heart valve sizing, positioning, and patient selection for TAVI in bicuspid aortic valve.
Why the study?
As TAVI expands to younger, lower-risk patients with bicuspid aortic valve, matching surgical outcomes requires identifying anatomically unsuitable patients and optimizing valve sizing and positioning.
Patient-specific computer simulation is an emerging technology that may improve patient selection, valve sizing, and positioning for TAVI in patients with bicuspid aortic valves.
May support TAVI planning in bicuspid valves; leaves open whether it improves outcomes in prospective trials.
Transcatheter aortic valve implantation (TAVI) is increasingly being used to treat younger, lower-risk patients, many of whom have bicuspid aortic valve (BAV). As TAVI begins to enter these younger patient cohorts, it is critical that clinical outcomes from TAVI in BAV are matched to those achieved by surgery. Therefore, the identification of patients who, on an anatomical basis, may not be suitable for TAVI, would be desirable. Furthermore, clinical outcomes of TAVI in BAV might be improved through improved transcatheter heart valve sizing and positioning. One potential solution to these challenges is patient-specific computer simulation. This review presents the methodology and clinical evidence surrounding patient-specific computer simulation of TAVI in BAV.
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Dowling et al. (2021) conducted a review in Bicuspid Aortic Valve (BAV) undergoing Transcatheter Aortic Valve Implantation (TAVI). Patient-specific computer simulation was evaluated. Patient-specific computer simulation is presented as a potential solution to improve transcatheter heart valve sizing, positioning, and patient selection for TAVI in bicuspid aortic valve.
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