Key result
The Morphology-Voltage-P-wave duration (MVP) score predicted atrial fibrillation recurrence within 1 year after pulmonary vein isolation (AUC 0.789; 95% CI 0.730-0.840; p < 0.001).
Why the study?
Long-term ablation success varies and a clinical scoring system to predict rhythm outcome remains an unmet need, prompting evaluation of the MVP score after PVI in PAF.
Does the MVP score predict atrial fibrillation recurrence after pulmonary vein isolation in patients with paroxysmal atrial fibrillation?
Cohort (n=207)
No
Does the MVP score predict atrial fibrillation recurrence after pulmonary vein isolation in patients with paroxysmal atrial fibrillation?
Effect estimate: AUC 0.789 (95% CI 0.730-0.840)
p-value: p=<.001
The MVP score is a useful and easy-to-measure ECG tool for predicting AF recurrence within 1 year after PVI in patients with paroxysmal AF.
May aid post-ablation AF recurrence risk stratification; hypothesis-generating and requires prospective validation before clinical use.
BACKGROUND: Atrial fibrillation (AF) is known to be the most common arrhythmia, and the successful rate of long-term ablation can vary comparatively. Therefore, a clinical scoring system to predict rhythm outcome remains a critical unmet need. The electrocardiographic (ECG) risk score which is named Morphology-Voltage-P-wave duration (MVP) score was reported to be useful for predicting new-onset AF. The goal of the current study was to investigate whether the MVP score was a useful scheme in the prediction of rhythm outcome following pulmonary vein isolation (PVI) in paroxysmal atrial fibrillation (PAF). METHODS: We retrospectively analyzed baseline characteristics, risk scores, and rates of AF recurrence 12 months postablation in the medical records of 207 consecutive patients with PAF undergoing PVI in General Hospital of Ningxia medical University from 2010 to 2018. RESULTS: Two hundred and seven patients (71 females, median age 58.7 years) with symptomatic PAF underwent PVI. From the cohort, 32.3% (67) had a recurrence of AF within 1 year of the PVI. The area of the MVP score under the curve in the receiver operating characteristics (ROC) analysis was 0.789 (95% CI 0.730-0.840, p < .001). A score cut-off value of >3 showed the best predictive ability for AF recurrence within 1 year after PVI, with sensitivity (53.03%) and specificity (89.87%). CONCLUSIONS: The results of our study suggest that the easy-to-measure ECG MVP score can be used to predict recurrence of PAF after PVI.
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Yang et al. (2020) conducted a cohort in Paroxysmal atrial fibrillation (PAF) (n=207). Morphology-Voltage-P-wave duration (MVP) score was evaluated on Atrial fibrillation recurrence within 1 year of pulmonary vein isolation (AUC 0.789, 95% CI 0.730-0.840, p=<.001). The Morphology-Voltage-P-wave duration (MVP) score predicted atrial fibrillation recurrence within 1 year after pulmonary vein isolation (AUC 0.789; 95% CI 0.730-0.840; p < 0.001).
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