January 1, 1980Biomedical ResearchOpen Access

Calcium Regulatory Mechanism in Vertebrate Smooth Muscle

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Population

Vertebrate smooth muscle (specifically avian gizzard and mammalian taenia coli)

Design

Review

Authors

YNYoshiaki NonomuraThe University of Tokyo SESetsuro EbashiThe University of Tokyo

Discussion

Member takes

Implication

Challenges phosphorylation-centric model in smooth muscle; leaves open validation in human vascular physiology.

Structured PICO

Population

Vertebrate smooth muscle (specifically avian gizzard and mammalian taenia coli)

This review summarizes the structural features of vertebrate smooth muscle myofilaments and proposes that calcium regulation occurs via the leiotonin-tropomyosin system rather than myosin light chain phosphorylation.

Cite This Study

Nonomura et al. (1980) studied this question.

synapsesocial.com/papers/6a7b0b3d14b028facf0ea856 https://doi.org/10.2220/biomedres.1.1

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