Key result
Heavy midlife alcohol consumption was associated with an increased risk of late-life cognitive impairment compared to light drinking (RR 1.94; 95% CI 1.10-3.44).
Why the study?
Does midlife alcohol consumption affect the risk of cognitive impairment in late life?
Population
1,486 subjects recruited from the Finnish Twin Cohort
Comparison
Midlife alcohol consumption vs Light drinking
Design
Cohort
Follow-up
mean 22.8 years
Authors
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Heavy midlife drinking may elevate late-life cognitive impairment risk; leaves open causality and optimal patterns.
Cohort (n=1,486)
Does midlife alcohol consumption affect the risk of cognitive impairment in late life?
Relative Risk: 1.94 (95% CI 1.1–3.44)
Light to moderate alcohol use in midlife is associated with a lower risk of cognitive impairment in late life compared to abstaining, heavy drinking, or binge drinking.
Virta et al. (2010) conducted a cohort in Cognitive impairment (n=1,486). Heavy alcohol consumption vs. Light alcohol consumption was evaluated on Cognitive impairment (RR 1.94, 95% CI 1.10-3.44). Heavy midlife alcohol consumption was associated with an increased risk of late-life cognitive impairment compared to light drinking (RR 1.94; 95% CI 1.10-3.44).
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