Key result
Among patients hospitalized for acute heart failure, the in-hospital death rate was 9.5%, with subsequent mortality rates of 7.5% and 11.5% at 3 and 12 months, respectively.
Observational (n=200)
No
This observational study highlights that acute heart failure patients often present with preserved systolic function and multiple comorbidities, experiencing high in-hospital and 1-year mortality despite guideline-directed management.
Answers are grounded in this paper and cite their sources.
Acute HF mortality remains high despite management; leaves open optimal strategies for comorbid patients with preserved EF.
Objective. To evaluate the causes of acute heart failure, complications, management, and outcomes.Material and methods. A total of 200 patients with diagnosed de novo acute heart failure (27.5%) or worsening chronic heart failure (72.5%) were treated at the Department of Cardiology, Hospital of Kaunas University of Medicine, which was participating in the Euro Heart Failure Survey-II (EHFS-II). The patients were divided into five groups: 1) chronic decompensated heart failure (66.0%); 2) pulmonary edema (13.0%); 3) hypertensive heart failure (7.5%); 4) cardiogenic shock (11.0%); and 5) right heart failure (2.5%). Results. Hypertensive and coronary heart diseases were the most common underlying conditions of acute heart failure. Noncompliance with the prescribed medications was present as the most frequent precipitating factor in more than half of the cases. Left ventricular ejection fraction of >45% was found in 28.64% of cases. Intravenous diuretics (74.5%), nitrates (44.0%), and heparin (71.0%) were the most widely used in the acute phase. At discharge from hospital, 96.69% of patients were given diuretics; 80.11%, angiotensin-converting enzyme inhibitors; and 62.43%, beta-blockers. The mean duration of inhospital stay was 13 days; death rate was 9.5%: after 3 months and 12 months, it was 7.5% and 11.5%, respectively. Conclusion. Preserved systolic function, multiple concomitant diseases, and high mortality rates were observed in a substantial proportion of the patients hospitalized due to acute heart failure. The management of the patients in a university hospital center was performed in accordance with the international guidelines.
No takes yet. Share an insight, caveat, or question.
Venskutonytė et al. (2009) conducted an observational in Acute heart failure (n=200). Acute heart failure was evaluated on In-hospital death rate. Among patients hospitalized for acute heart failure, the in-hospital death rate was 9.5%, with subsequent mortality rates of 7.5% and 11.5% at 3 and 12 months, respectively.
Synapse has enriched 10 related papers. Consider them for comparative context: