What is the clinical evidence from this study?

Study design: Cohort. Population: Acute heart failure (n=312). Primary outcome: 12-month all-cause mortality.

What question did this study set out to answer?

To characterize the clinical presentation, short- and long-term mortality rates, and prognostic risk factors among patients hospitalized with acute heart failure.

May 28, 2005European Journal of Heart Failure

Acute Heart Failure: Clinical Presentation, One-Year Mortality and Prognostic Factors

Q: What does this research mean for the field?

Patients hospitalized with acute heart failure experience high mortality despite modern treatment, with a 30-day mortality of 11% and a 12-month all-cause mortality of 29%. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

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Key result

Patients hospitalized with acute heart failure experienced high mortality, with a 30-day mortality of 11% and a 12-month all-cause mortality of 29%.

Key Points

To characterize the clinical presentation, short- and long-term mortality rates, and prognostic risk factors among patients hospitalized with acute heart failure.
Conducted a prospective study enrolling 312 consecutive patients with acute heart failure (symptom onset or worsening within 7 days) across two European centers.
Evaluated baseline clinical characteristics, underlying heart conditions, precipitating triggers, left ventricular ejection fraction, and need for intensive care.
Coronary heart disease was the leading underlying etiology, with elevated blood pressure (>150 mmHg) and acute ischemia serving as primary triggers, and 39% requiring ICU admission.
Thirty-day mortality was 11% (higher with shock or elevated troponin T), and 12-month all-cause mortality reached 29% (higher with shock, left ventricular dysfunction, renal insufficiency, coronary heart disease, and advancing age).

Study Design

Type

Cohort (n=312)

Multicenter

Yes

Structured PICO

Population

312 consecutive patients from two European centers hospitalised with acute HF (defined as new onset or worsening of symptoms and signs of HF within 7 days), mean age 73 years, 56% men.

Outcome

30-day mortality and 12-month all-cause mortalityhard clinical

Patients hospitalized with acute heart failure continue to face high short- and long-term mortality rates, driven by factors such as cardiogenic shock, left ventricular dysfunction, and renal insufficiency.

Discussion

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Implication

Acute HF hospitalization signals high short- and long-term mortality; leaves open identification of modifiable predictors in contemporary cohorts.

Cite This Study

Rudiger et al. (2005) conducted a cohort in Acute heart failure (n=312). Patients hospitalized with acute heart failure experienced high mortality, with a 30-day mortality of 11% and a 12-month all-cause mortality of 29%.

synapsesocial.com/papers/6a16b93cb13aec50ea6b7168 https://doi.org/10.1016/j.ejheart.2005.01.014

Topics

HFrEF treatment Heart failure Heart failure hospitalization HFpEF management

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Implication

Acute HF hospitalization signals high short- and long-term mortality; leaves open identification of modifiable predictors in contemporary cohorts.

Acute Heart Failure: Clinical Presentation, One-Year Mortality and Prognostic Factors

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Topics

Acute Heart Failure: Clinical Presentation, One-Year Mortality and Prognostic Factors

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider