May 1, 1996Experimental PhysiologyOpen Access

Reflex vascular responses from aortic arch, carotid sinus and coronary baroreceptors in the anaesthetized dog

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Population

Chloralose-anaesthetized dogs

Comparison

Independent application of pressure to coronary… vs Comparison of responses between coronary…

Design

Preclinical

Authors

NMN. C. McMahonGlaxoSmithKline (United Kingdom)MDMJ DrinkhillUniversity of Leeds RHR. HainsworthBoston Children's Hospital

Discussion

Member takes

Implication

Delayed coronary baroreceptor response may affect BP regulation; leaves open their distinct role in human hypertension.

Structured PICO

Population

Chloralose-anaesthetized dogs

Intervention

Independent application of pressure to coronary, carotid, and aortic baroreceptors

Comparator

Comparison of responses between coronary, carotid, and aortic baroreceptors

Outcome

Reflex vascular responses (vasodilatation magnitude and vasoconstriction recovery time)surrogate

Coronary baroreceptors exhibit a uniquely delayed vasoconstrictor recovery response following hypertension compared to carotid and aortic baroreceptors, which may impact arterial blood pressure control.

Limitations

Mechanism responsible for delaying the vasoconstriction following a period of coronary hypertension is not known

Cite This Study

McMahon et al. (1996) studied this question.

synapsesocial.com/papers/6a7b145614b028facf0eac4d https://doi.org/10.1113/expphysiol.1996.sp003944

View Full Paper

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Bookmark

Reflex vascular responses from aortic arch, carotid sinus and coronary baroreceptors in the anaesthetized dog

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Reflex vascular responses from aortic arch, carotid sinus and coronary baroreceptors in the anaesthetized dog

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider