This article describes a technique for obtaining adult stem cells from bone marrow aspirate. Case reports show how this procedure might replace the gold standard for bone grafts with the platinum standard of obtaining stem cells. The bone marrow aspirate and transplantation of adult stem cells within the resorbable) matrix and under the influence of soluble regulators have the potential for introducing the platinum standard for bone grafts. There are several advantages to using bone marrow aspirate. The technique is simple, a second surgical site is not needed, there is minimal postoperative morbidity, and adult stem cells populate the graft site with osteoblasts.
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Smiler et al. (2006) studied this question.
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