Key result
Percutaneous patent foramen ovale closure requires tailored techniques based on anatomical variations, with future developments focusing on minimalistic approaches to reduce foreign material.
A tailored approach to PFO closure based on specific anatomical variations is necessary, with future trends favoring devices that leave less foreign material.
May warrant anatomy-specific PFO closure now; leaves open the value of minimalistic devices in prospective trials.
Technological developments in recent years have made percutaneous patent foramen ovale (PFO) closure a feasible and safe treatment option. Procedural competency demands a thorough understanding on the variations of PFO anatomy, which can broadly be classified into PFO with minimal tunnel, PFO with long tunnel and PFO associated with atrial septal aneurysm. Each of these subtypes requires different techniques to achieve successful PFO closure and it is unlikely that a single ‘ideal’ device will be suitable for all subtypes. Recognizing the potential problems associated with bulky metallic devices, current developments are focused on a minimalistic approach to PFO closure with reduced foreign material left on the inter-atrial septum. With further refinements, these novel technologies will likely take up a major role in the treatment of PFO-related diseases in the future.
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Ko et al. (2010) conducted a review in Patent foramen ovale (PFO). Percutaneous patent foramen ovale (PFO) closure was evaluated. Percutaneous patent foramen ovale closure requires tailored techniques based on anatomical variations, with future developments focusing on minimalistic approaches to reduce foreign material.
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