Key result
Transcatheter aortic valve implantation significantly improved the apnoea-hypopnoea index in patients with central sleep apnoea from 43.5 to 19.4 events/hr (p<0.001).
Why the study?
Does transcatheter aortic valve implantation (TAVI) improve central sleep apnoea in patients with severe aortic stenosis?
Observational (n=29)
Does transcatheter aortic valve implantation (TAVI) improve central sleep apnoea in patients with severe aortic stenosis?
Absolute Event Rate: 19.4% vs 43.5%
p-value: p=<0.001
TAVI significantly improves central sleep apnea and overall sleep-disordered breathing in high-risk patients with severe aortic stenosis.
TAVI was associated with reduced central sleep apnoea severity; leaves open whether this improves outcomes or warrants routine assessment in severe aortic stenosis.
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Linhart et al. (2013) conducted an observational in Severe aortic stenosis and high surgical risk (n=29). Transcatheter aortic valve implantation (TAVI) vs. Baseline (before TAVI) was evaluated on Apnoea-hypopnoea index (AHI) in the central sleep apnoea (CSA) group (p=<0.001). Transcatheter aortic valve implantation significantly improved the apnoea-hypopnoea index in patients with central sleep apnoea from 43.5 to 19.4 events/hr (p<0.001).
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