Why the study?
Does measuring right ventricular output via dye-dilution curves from the pulmonary artery agree with brachial arterial curves and the direct Fick method in normal subjects?
Does measuring right ventricular output via dye-dilution curves from the pulmonary artery agree with brachial arterial curves and the direct Fick method in normal subjects?
Measuring right ventricular output via dye-dilution curves from the pulmonary artery is a valid method that agrees with the direct Fick method within ±15%.
Supports dye-dilution from pulmonary artery for RV output in normals; leaves open validation in disease states.
Indicator dilution curves have been inscribed through a cardiac catheter from the pulmonary artery in nine normal subjects. The suitability of these curves for measuring the right ventricular output has been investigated by comparing the calculated values of flow with those obtained from brachial arterial curves and from application of the direct Fick. The results indicate that both the pulmonary and brachial arterial flows agree with the Fick within ±15%. The advantages of using the pulmonary artery as a sampling site are stressed. These include a) the absence of a capillary bed between the injection and sampling points, and b) a considerable reduction in the contamination of the primary curve by recirculating indicator. The theoretical possibility of individually measuring the outputs of the right and left ventricles is also discussed. Submitted on August 2, 1957
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Fritts et al. (1957) studied this question.
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