What question did this study set out to answer?

To evaluate whether the initiation of antihypertensive medications is linked to an immediate increase in hip fracture risk among older adults.

November 19, 2012Archives of Internal Medicine

The Risk of Hip Fracture After Initiating Antihypertensive Drugs in the Elderly

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Authors

DBDebra A. ButtUniversity of Toronto MMMuhammad MamdaniVascular Medicine PAPeter C. AustinHeart Failure & Transplant

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Implication

Population-based self-controlled case series reveals an increased risk of hip fracture after starting antihypertensives in older adults, highlighting the need for fall precautions during treatment...

Key Points

To evaluate whether the initiation of antihypertensive medications is linked to an immediate increase in hip fracture risk among older adults.
Conducted a population-based, self-controlled case series using health care administrative databases in Ontario, Canada, among N=301,591 newly treated hypertensive older adults from 2000 to 2009.
Defined the risk period as the first 45 days after antihypertensive initiation, comparing hip fracture incidence against pre- and post-treatment control periods within a 450-day observation window.
Identified 1,463 incident hip fractures during the 450-day observation window across the cohort.
Demonstrated a 43% increased risk of hip fracture during the first 45 days of treatment initiation compared with control periods (incidence rate ratio, 1.43; 95% CI, 1.19–1.72).

Cite This Study

Butt et al. (2012) studied this question.

synapsesocial.com/papers/6a7b54cc756812e39589f762 https://doi.org/10.1001/2013.jamainternmed.469

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Implication

Population-based self-controlled case series reveals an increased risk of hip fracture after starting antihypertensives in older adults, highlighting the need for fall precautions during treatment...

The Risk of Hip Fracture After Initiating Antihypertensive Drugs in the Elderly

Discussion

Member takes

Implication

Key Points

Cite This Study

The Risk of Hip Fracture After Initiating Antihypertensive Drugs in the Elderly

Discussion

Member takes

Implication

Key Points

Cite This Study

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