Key result
Elimination of ATP-induced atrial fibrillation by additional radiofrequency ablation yielded a higher success rate than in patients without ATP-induced AF (86.2% vs 67.3%; P=0.04).
Why the study?
Does additional radiofrequency ablation of ATP-induced non-pulmonary vein foci improve procedural success rates in patients with paroxysmal AF undergoing CPVI?
Cohort (n=300)
Does additional radiofrequency ablation of ATP-induced non-pulmonary vein foci improve procedural success rates in patients with paroxysmal AF undergoing CPVI?
Absolute Event Rate: 86.2% vs 67.3%
p-value: p=0.04
Eliminating ATP-induced AF triggers (predominantly in the superior vena cava) with additional ablation after CPVI significantly improves procedural success rates in paroxysmal AF.
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Additional ablation of ATP-induced non-PV foci may improve paroxysmal AF success after CPVI; leaves open need for randomized confirmation before practice change.
Zhang et al. (2014) conducted a cohort in Paroxysmal atrial fibrillation (n=300). Elimination of ATP-induced AF by additional RF ablation vs. Non-ATP inducible group was evaluated on Procedural success rate (p=0.04). Elimination of ATP-induced atrial fibrillation by additional radiofrequency ablation yielded a higher success rate than in patients without ATP-induced AF (86.2% vs 67.3%; P=0.04).
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