Key result
Minimally invasive pulmonary vein isolation resulted in an absolute reduction in AF burden of 65% (95% CI 42-88, P < 0.001) at 12 months compared to preoperative baseline.
Why the study?
Does minimally invasive pulmonary vein isolation reduce AF burden in patients with paroxysmal atrial fibrillation?
Observational (n=20)
Does minimally invasive pulmonary vein isolation reduce AF burden in patients with paroxysmal atrial fibrillation?
Minimally invasive pulmonary vein isolation significantly reduces AF burden in patients with paroxysmal AF, and continuous loop monitoring provides an accurate method for assessing surgical success.
Minimally invasive PVI was associated with AF burden reduction; leaves open efficacy in paroxysmal AF pending RCTs.
OBJECTIVES: Surgical ablation is a well-known treatment for atrial fibrillation (AF); however, little is known about the absolute success rate. The aim of this study is to compare the absolute pre- and postoperative incidence of AF after minimally invasive surgical ablation for paroxysmal AF. METHODS: Twenty consecutive patients (mean age 55 ± 8; 55% male) received a continuous loop monitor (CLM) 4 weeks prior to a minimally invasive pulmonary vein isolation (MIPVI). The mean preoperative AF burden was compared with the mean AF burden during follow-up. Follow-up was achieved for a period of 12 months. RESULTS: Seventeen patients underwent an MIPVI successfully. Two patients did not reach the threshold for surgery. In 1 patient, surgery was discontinued because of a perioperative bleeding due to adhesions after a previous percutaneous AF ablation. Mean AF burden preoperatively was 66%. After 12 months, there was an absolute reduction in AF burden of 65% (95% CI 42-88, P < 0.001) and 12 of 15 patients in follow-up (80%) were free of AF without antiarrhythmic drugs (AADs). CONCLUSIONS: The use of a CLM in the follow-up of surgical ablation is a very accurate way to confirm absolute surgical results. Furthermore, with the use of a CLM, preoperative evaluation can be done more accurately, and the surgical procedure can be adjusted to the patients' needs.
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Oudeman et al. (2015) conducted an observational in Paroxysmal atrial fibrillation (n=20). Minimally invasive pulmonary vein isolation (MIPVI) vs. Preoperative baseline was evaluated on AF burden (absolute reduction 65%, 95% CI 42-88, p=<0.001). Minimally invasive pulmonary vein isolation resulted in an absolute reduction in AF burden of 65% (95% CI 42-88, P < 0.001) at 12 months compared to preoperative baseline.
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