Key result
A finite element method of a monodomain model coupled with the modified FitzHugh-Nagumo model was developed to simulate cardiac excitation isotropic propagation.
The study presents a computational approach using the finite element method to simulate the electrical activity and action potential propagation in human cardiac tissues.
Advances computational cardiac modeling; leaves open experimental validation before any clinical use.
The modeling of the electrical activity of the heart is of great medical and scientific interest as it provides a way to better understand the underlying biophysical phenomena supports the development of new techniques for diagnoses and serves as a platform for drug tests. At cellular level, the electrical activity of cardiac tissues may be simulated by solving a system of ordinary deferential equations (ODEs) describing the electrical behavior of the cell membrane. Because the biophysical processes underlying this phenomenon are non-linear and change very rapidly, the ODE system is challenging to solve numerically. Furthermore, the implementation of these models is a hard task. In this paper we present a finite element method (FEM) of monodomain model which coupled with the modified FitzHugh-Nagumo (FHN) model in simulation of cardiac excitation isotropic propagation.
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Shuaiby et al. (2011) studied this question. Finite element method (FEM) of monodomain model coupled with modified FitzHugh-Nagumo (FHN) model was evaluated on Simulation of cardiac excitation isotropic propagation. A finite element method of a monodomain model coupled with the modified FitzHugh-Nagumo model was developed to simulate cardiac excitation isotropic propagation.
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