Key result
Substance use (opium and methamphetamine) was associated with significantly poorer performance in MMSE scores for orientation, attention, and mental status compared to normal individuals (P < .05).
Why the study?
Substance use can have adverse repercussions on mental status, leading to a need to compare the mental status of substance abusers with normal individuals.
Does substance use (methamphetamine or opium) impair mental status as measured by MMSE compared to non-substance users?
Cross-Sectional (n=202)
No
Does substance use (methamphetamine or opium) impair mental status as measured by MMSE compared to non-substance users?
Substance use, including opium and methamphetamine, is associated with poorer cognitive performance on the MMSE compared to healthy controls.
Answers are grounded in this paper and cite their sources.
Substance users show lower MMSE scores; leaves open causality and clinical relevance pending longitudinal data.
Background: Due to its progressive nature, substance use impacts the entire aspects of life, and can result in adverse repercussions on mental status. Accordingly, the current article seeks to compare the mental status of substance abusers with that of normal individuals.Methods: The study is a cross-sectional research. The study population is comprised of 50 methamphetamine users, 52 opium users, and 100 normal individuals referred to Farabi Psychiatric Hospital in Kermanshah, 2018, in Iran. The subjects were selected by convenience sampling method and matched in terms of demographic characteristics. Data collection was performed using Mental State Examination (MMSE) and demographic questionnaire.Results: The results showed that mean scores of orientation, attention, and mental status were significantly different between the normal and substance abusers (P < .05). However, the above-mentioned difference was not significant between methamphetamine abusers and opioid abusers (P > .05). In addition, the mean score of the language tests was statistically significant only among the normal and methamphetamine abusers (P < .05).Conclusions: Based on the obtained results, it can be concluded that the opium and methamphetamine users showed poorer performance in MMSE than the normal group.
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Shakeri et al. (2020) conducted a cross-sectional in Substance use (n=202). Substance use (methamphetamine or opium) vs. Normal individuals (non-substance users) was evaluated on Mental State Examination (MMSE) scores (p=< .05). Substance use (opium and methamphetamine) was associated with significantly poorer performance in MMSE scores for orientation, attention, and mental status compared to normal individuals (P < .05).
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