Key result
Hypertension (OR 2.315) and diabetes (OR 1.878) were independent risk factors for anterior intracranial atherosclerotic disease in patients with acute ischemic stroke.
Why the study?
Intracranial atherosclerotic disease is a prevalent cause of ischemic stroke related to recurrent strokes, motivating the identification of ICAD rates and risk factors in Turkish patients with acute ischemic stroke.
Observational (n=862)
No
Odds Ratio: 2.315 (95% CI 1.064–5.036)
p-value: p=0.034
In Turkish patients with acute ischemic stroke, intracranial atherosclerotic disease is present in 20%, with hypertension and diabetes driving anterior disease, while advanced age, diabetes, hyperlipidemia, and vertebral artery hypoplasia drive posterior disease.
Distinct risk profiles for anterior versus posterior ICAD in stroke; extends prior observations but remains hypothesis-generating and should not yet change practice.
Background & Objective: Intracranial atherosclerotic disease (ICAD) is a prevalent cause of ischemic stroke and is related to recurrent strokes. In this study, we aim to identify the ICAD rate and establish the risk factors in patients with acute ischemic stroke (AIS) in our population in Turkey. Methods: Eight hundred sixty-two patients diagnosed with AIS in our tertiary centre between 01-01.2019 and 01.01.2021 were retrospectively included in this study. Results: We detected ICAD in 172 (20%) patients. While the independent risk factors of anterior ICAD were hypertension and diabetes mellitus, the risk factors of posterior ICAD were advanced age, diabetes mellitus, hyperlipidaemia and vertebral artery hypoplasia. There were more frequent posterior ICAD. Conclusion: There was difference in the risk factors for anterior ICAD and posterior ICAD in this Turkish study.
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Dinç et al. (2023) conducted an observational in Acute ischemic stroke (n=862). Hypertension vs. Absence of hypertension was evaluated on Anterior intracranial atherosclerotic disease (OR 2.315, 95% CI 1.064-5.036, p=0.034). Hypertension (OR 2.315) and diabetes (OR 1.878) were independent risk factors for anterior intracranial atherosclerotic disease in patients with acute ischemic stroke.
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