Key result
Slow AV nodal pathway cryoablation achieved a 100% success rate with no complications or recurrences over a median 16-month follow-up in 7 children weighing under 15 kg.
Why the study?
AVNRT uncommonly presents during infancy, and catheter ablation is rarely indicated in children <15 kg despite demonstrated safety in pediatric populations.
Does slow AV nodal pathway cryoablation safely and effectively treat AVNRT in children under 15 kg?
Observational (n=7)
Does slow AV nodal pathway cryoablation safely and effectively treat AVNRT in children under 15 kg?
Cryoablation of the slow AV nodal pathway is safe and effective for treating AVNRT in small children weighing less than 15 kg.
Supports cryoablation feasibility for AVNRT in small children; hypothesis-generating and requires larger prospective confirmation.
BACKGROUND: Atrioventricular nodal reentrant tachycardia (AVNRT) does not commonly present during infancy. Although relative safety of catheter ablation of AVNRT has been demonstrated in pediatrics, this procedure is rarely indicated in children <15 kg. METHODS: Retrospective review of seven cases of AVNRT that presented in children younger than 1 year of age and required catheter ablation for definitive management. Electrophysiology (EP) study was planned with two or three catheters. Area of ablation determined by voltage mapping, propagation sinus wave collision and slow pathway potential location. Ablation performed with cryothermal energy. No fluoroscopy was used. RESULTS: Presentation ranged from 36 weeks of gestation to 11 months of age. Two presented in fetal life and two in the neonatal period. The median age of ablation was 20 months (range 17-31 months). The median weight at ablation was 11.4 kg (range 8.9-14.9 kg). Median follow-up time was 16 months. All had typical AVNRT. The median tachycardia cycle length was 216 ms. 100% successful rate using cryoablation. No complications. No recurrence of tachycardia during the follow-up period. CONCLUSION: Slow AV nodal pathway cryoablation may be safely performed, with good short and medium-term outcomes in patients under 15 kg.
No takes yet. Share an insight, caveat, or question.
Jimenez et al. (2023) conducted an observational in Atrioventricular nodal reentrant tachycardia (AVNRT) (n=7). Slow AV nodal pathway cryoablation was evaluated on Procedural success rate. Slow AV nodal pathway cryoablation achieved a 100% success rate with no complications or recurrences over a median 16-month follow-up in 7 children weighing under 15 kg.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: