Key result
The EEG-based Narcotrend Index correlated significantly with the heart rate variability parameter SDNN (rrm = 0.2) across all measures during general anesthesia.
Why the study?
The study was conducted to investigate the level of concordance between heart rate variability, the EEG-based Narcotrend Index for anesthesia depth, and sevoflurane minimal alveolar concentration across a surgical procedure.
Population
31 male patients during robotic-assisted radical prostatectomy
Design
Non-blinded cross-sectional study
Authors
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May support HRV as marker of autonomic balance under anesthesia; leaves open clinical utility pending prospective trials.
Cross-Sectional (n=31)
non-blinded
No
Effect estimate: rrm = 0.2 (95% CI 0.101-0.303)
p-value: p=≤0.001
Intraoperative heart rate variability significantly correlates with the Narcotrend Index and sevoflurane concentration, suggesting it can provide essential information about autonomic nervous system homeostasis during general anesthesia.
Keim et al. (2023) conducted a cross-sectional in General anesthesia during radical prostatectomy (n=31). General anesthesia with sevoflurane was evaluated on Concordance between the Narcotrend Index and the standard deviation of the means of RR intervals (SDNN) (rrm = 0.2, 95% CI 0.101-0.303, p=≤0.001). The EEG-based Narcotrend Index correlated significantly with the heart rate variability parameter SDNN (rrm = 0.2) across all measures during general anesthesia.
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