Key result
In patients with Type 2 diabetes mellitus, body mass index showed a significant positive correlation with total cholesterol (r=0.93), LDL (r=0.93), and triglycerides (r=0.94), and a negative correlation with HDL (r=-0.96).
Why the study?
Dyslipidemia and obesity are considered cardinal features of T2DM, prompting investigation into the relationship between BMI and serum lipid profiles in these patients.
Does BMI correlate with dyslipidemia in patients with Type 2 diabetes mellitus?
Case-Control (n=400)
No
Does BMI correlate with dyslipidemia in patients with Type 2 diabetes mellitus?
Higher body mass index is strongly correlated with worsening dyslipidemia, characterized by elevated total cholesterol, triglycerides, and LDL, and reduced HDL, in patients with Type 2 diabetes mellitus.
Answers are grounded in this paper and cite their sources.
May link BMI to dyslipidemia in T2DM; hypothesis-generating and should not yet change practice.
T2DM is a chronic disease characterized by hyperglycemia as a result of insulin dysfunction. Both Dyslipidemia and obesity are considered cardinal features of T2DM. Aims: To study the relationship of BMI with serum lipid profile in T2DM patients.Methods: The study consisted of 200 T2DM patients and 200 control individuals. Phenotypic parameters included are body mass index (BMI), and fasting blood sugar (FBS) and lipid profile.Results :The statistical analyses used to analyze the data.A significant positive correlation of serum TC, TG and LDL levels and significantly negative correlation of serum HDL levels with BMI in patients with T2DM (p<0.001).Conclusion: Dyslipidemiaare associated with BMI in T2DM.
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Nasser et al. (2019) conducted a case-control in Type 2 diabetes mellitus (n=400). Body mass index (BMI) vs. Non-diabetic controls was evaluated on Correlation of BMI with total cholesterol in T2DM patients (r=0.93, p=<0.001). In patients with Type 2 diabetes mellitus, body mass index showed a significant positive correlation with total cholesterol (r=0.93), LDL (r=0.93), and triglycerides (r=0.94), and a negative correlation with HDL (r=-0.96).
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