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December 1, 1998Genes & DevelopmentOpen Access

c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

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Authors

GLGil LevkowitzAmerican Committee for the Weizmann Institute of ScienceHWHadassa WatermanWeizmann Institute of ScienceEZEli ZamirGerman Cancer Research Center

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Cite This Study

Levkowitz et al. (1998) studied this question.

synapsesocial.com/papers/6a7ba0d6c2a640f0bcdf7930https://doi.org/10.1101/gad.12.23.3663
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1c-Cbl Is Transiently Tyrosine-phosphorylated, Ubiquitinated, and Membrane-targeted following CSF-1 Stimulation of Macrophages1996 · 162 citations
  2. 2The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor1991 · 288 citations
  3. 3Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors.1993 · 156 citations
  4. 4Multiple autophosphorylation sites of the epidermal growth factor receptor are essential for receptor kinase activity and internalization. Contrasting significance of tyrosine 992 in the native and truncated receptors.1992 · 150 citations