Key result
Moderate aerobic physical exercise may reduce oxidative stress and inflammation, potentially improving endothelial homeostasis, mood, and cognition in vascular depression and cognitive impairment.
Why the study?
Oxidative stress-related endothelial damage contributes to vascular depression and dementia, while aerobic exercise may reduce oxidative stress, improve endothelial homeostasis, mood, and cognition.
Does moderate aerobic physical exercise improve endothelial homeostasis, mood, and cognition in patients with vascular depression and vascular cognitive impairment?
Does moderate aerobic physical exercise improve endothelial homeostasis, mood, and cognition in patients with vascular depression and vascular cognitive impairment?
Moderate aerobic physical exercise may reduce oxidative stress and inflammation, improving endothelial homeostasis, mood, and cognition in vascular depression and cognitive impairment.
Answers are grounded in this paper and cite their sources.
Exercise may mitigate oxidative endothelial damage in vascular depression; leaves open definitive trials for cognitive outcomes.
Oxidative stress- (OS-) related endothelial damage is involved in the occurrence and progression of several disorders, such as vascular depression and dementia. It has been reported that moderate, aerobic, physical exercise could reduce OS and inflammation, thus limiting the cardiovascular risk factors while improving endothelial homeostasis, mood, and cognition. In this review, we will discuss about the role of OS and OS-related endothelial damage in vascular depression and vascular cognitive impairment. Then, we will comment on the effects of physical exercise on both disorders.
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Luca et al. (2019) conducted a review in Vascular depression and vascular cognitive impairment. Aerobic physical exercise was evaluated. Moderate aerobic physical exercise may reduce oxidative stress and inflammation, potentially improving endothelial homeostasis, mood, and cognition in vascular depression and cognitive impairment.
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