Key result
In children with Kawasaki disease, the symptom of vomiting was significantly more frequent in intravenous immunoglobulin non-responders compared to responders (70.0% vs 13.5%, p=0.004).
Population
121 children treated for Kawasaki disease at Presbyterian medical center from January 2005 to June 2010
Design
Cohort
Authors
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Vomiting was associated with IVIG nonresponse in Kawasaki disease; hypothesis-generating for risk stratification and requires prospective validation.
Observational (n=121)
No
Absolute Event Rate: 70% vs 13.5%
p-value: p=0.004
A high proportion of children with Kawasaki disease present with nonspecific associated symptoms, which physicians must recognize to prevent delayed diagnosis and coronary complications.
Yun et al. (2011) conducted an observational in Kawasaki disease (n=121). Intravenous immunoglobulin (IVIG) non-response vs. IVIG response was evaluated on Incidence of vomiting (p=0.004). In children with Kawasaki disease, the symptom of vomiting was significantly more frequent in intravenous immunoglobulin non-responders compared to responders (70.0% vs 13.5%, p=0.004).
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