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September 18, 2021World Journal of CardiologyOpen Access

Coronary vasospasm: A narrative review

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Key result

Coronary artery vasospasm is an underdiagnosed cause of acute chest pain that can lead to serious complications, with calcium channel blockers serving as the first-line treatment.

Why the study?

Pathophysiology of coronary artery vasospasm remains incompletely understood, its exact prevalence is not entirely clear, and optimal diagnostic and treatment strategies continue to evolve.

Design

Narrative review

Authors

JJJacob JewulskiSKSumesh KhanalKDKhagendra Dahal

Discussion

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Member takes

Overview

Coronary artery vasospasm warrants consideration in acute chest pain; leaves open questions on mechanisms and targeted therapies.

PICO

P
Population
Coronary artery vasospasm
I
Intervention / Comparator
Coronary artery vasospasm management

Coronary artery vasospasm is an important cause of acute chest pain syndrome that requires high clinical suspicion, provocative testing for diagnosis, and treatment with calcium channel blockers and nitrates.

Limitations

  • Pathophysiology of the disease remains incompletely understood
  • Exact prevalence is not entirely clear due to the dynamic nature of the disease
  • Timing criteria for escalated therapy require further investigation
  • Role of pharmaceuticals targeting oxidative stress remains incompletely understood

Cite This Study

Jewulski et al. (2021) conducted a review in Coronary artery vasospasm. Coronary artery vasospasm management was evaluated. Coronary artery vasospasm is an underdiagnosed cause of acute chest pain that can lead to serious complications, with calcium channel blockers serving as the first-line treatment.

synapsesocial.com/papers/6a7bb6f7ae178dbf17c6356ahttps://doi.org/10.4330/wjc.v13.i9.456
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