Echocardiographic automated border detection enables the assessment of load-independent indices of left ventricular function using pressure-area relationships.
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May support noninvasive load-independent LV assessment; leaves open prospective outcome validation.
Echocardiographic automated border detection is the ability to assess left ventricular (LV) cross-sectional cavity areas and volumes on line. This capability has enabled the use of LV pressure-volume relationships as a means to determine LV function in a manner relatively independent of loading conditions. This discussion reviews previous validation studies in animal models and humans using LV cross-sectional area as a surrogate for LV volume and the clinical applications of LV pressure-area relations. Applications of arterial pressure as a substitute for LV ejection pressure to assess pressure-area relations are also reviewed, along with the use of pressure-area relations to assess right ventricular performance. Last, preload-adjusted maximal power as an alternative load-insensitive means to determine LV performance is discussed.
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John Gorcsan (1999) studied this question.
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