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September 7, 2009Acta Anaesthesiologica Scandinavica

A ScvO2 cut-off of >=64% predicted CITD > 2.5 l/min/m2 with a positive predictive value of 91% (95% CI 79-98) and negative predictive value of 91% (95% CI 59-100).

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Why the study?

Does central venous oxygen saturation accurately detect low cardiac output in adult patients with septic shock?

Population

56 adult patients with septic shock in three general intensive care units, mean SOFA score 12, scheduled for…

Comparison

Measurement of central venous oxygen saturation… vs Thermodilution measurement of cardiac index (CITD)

Design

Cohort

Authors

APAnders PernerNHNicolai HaaseJWJørgen Wiis

Discussion

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Overview

ScvO2 >=64% may identify adequate cardiac index in septic shock; leaves open prospective validation before clinical adoption.

Structured PICO

Does central venous oxygen saturation accurately detect low cardiac output in adult patients with septic shock?

P
Population
56 adult patients with septic shock in three general intensive care units (ICUs), mean SOFA score 12, scheduled for catheter insertion for thermodilution measurement of cardiac index.
I
Intervention
Measurement of central venous oxygen saturation in the superior vena cava (ScvO2)
C
Comparator
Thermodilution measurement of cardiac index (CITD)
O
Outcome
Diagnostic accuracy (positive and negative predictive values) of ScvO2 for detecting cardiac index > 2.5 l/min/m2surrogate

In patients with septic shock, a central venous oxygen saturation of >=64% accurately predicts a cardiac index >2.5 l/min/m2, providing a simple screening tool for low cardiac output.

Cite This Study

Perner et al. (2009) studied this question.

synapsesocial.com/papers/6a7bc08f050daa66a5df7572https://doi.org/10.1111/j.1399-6576.2009.02086.x
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