Key result
Statins show promise as adjuvant or alternative therapy for erectile dysfunction resistant to PDE5 inhibitors.
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Erectile dysfunction is a common disorder that involves impairment of the vascular endothelium and has been associated with cardiovascular disease. Despite the general effectiveness of phosphodiesterase type 5 (PDE5) inhibitors, some erectile dysfunction patients are resistant to or do not tolerate treatment with them, thus requiring further treatment alternatives. Statins have emerged as a promising therapeutic option due to their multiple modes of action. The use of statins as adjuvant or alternative therapy in erectile dysfunction has opened new avenues for the treatment of this disorder.
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Ferrer et al. (2007) conducted a review in Erectile dysfunction. Statins was evaluated. Statins have emerged as a promising adjuvant or alternative therapy for erectile dysfunction, particularly for patients resistant to or intolerant of PDE5 inhibitors.
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