Key result
Time to surgery from last DOAC dose did not significantly affect 30-day mortality (OR 1.37; 95% CI 0.80-2.33; P=0.248) in geriatric hip fracture patients.
Why the study?
Timely surgical intervention in hip fracture improves outcomes, but evidence-based guidelines regarding surgical timing for patients on DOACs are lacking.
Does the timing of surgery from the last DOAC dose affect 30-day mortality in geriatric hip fracture patients?
Population
112 geriatric hip fracture patients aged 65 and over taking DOACs
Comparison
Timing of surgery from last DOAC dose
Design
Retrospective database/registry review
Follow-up
30 days
Authors
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DOAC use may delay hip fracture surgery; leaves open optimal timing and mortality effects pending prospective trials.
Cohort (n=112)
Does the timing of surgery from the last DOAC dose affect 30-day mortality in geriatric hip fracture patients?
Odds Ratio: 1.37 (95% CI 0.8–2.33)
p-value: p=0.248
In geriatric hip fracture patients on DOACs, the timing of surgery from the last dose did not significantly influence 30-day mortality, serious adverse events, or transfusion needs.
Tarrant et al. (2020) conducted a cohort in geriatric hip fracture (n=112). Time to surgery from last DOAC dose was evaluated on 30-day mortality (OR 1.37, 95% CI 0.80-2.33, p=0.248). Time to surgery from last DOAC dose did not significantly affect 30-day mortality (OR 1.37; 95% CI 0.80-2.33; P=0.248) in geriatric hip fracture patients.
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