Why the study?
To evaluate the effects of OAGB, RYGB, and SG on cardiometabolic risk factors in patients with severe obesity.
Do different bariatric surgery procedures (OAGB, RYGB, SG) differentially improve cardiometabolic risk factors in patients with severe obesity?
Population
485 patients with severe obesity
Comparison
OAGB vs RYGB vs SG
Design
Retrospective cohort study
Follow-up
12-months
Key result
Roux-en-Y gastric bypass resulted in a significantly greater percentage of total weight loss compared to sleeve gastrectomy (MD -2.33%, p=0.001) at 12 months in patients with severe obesity.
Authors
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RYGB/OAGB may yield greater weight/fat loss than SG; hypothesis-generating and should not yet change practice without RCTs.
Cohort (n=485)
None
Non-randomized
No
Do different bariatric surgery procedures (OAGB, RYGB, SG) differentially improve cardiometabolic risk factors in patients with severe obesity?
Mean Difference: -2.33
p-value: p=0.001
Bariatric surgery significantly improves cardiometabolic risk factors in severe obesity at 12 months, with RYGB and OAGB providing greater weight and fat mass loss than SG.
Tabesh et al. (2022) conducted a cohort in Severe obesity (n=485). Roux-en-Y gastric bypass (RYGB) and One anastomosis gastric bypass (OAGB) vs. Sleeve gastrectomy (SG) was evaluated on Percentage total weight loss (%TWL) at 12 months (SG vs RYGB) (MD -2.33%, p=0.001). Roux-en-Y gastric bypass resulted in a significantly greater percentage of total weight loss compared to sleeve gastrectomy (MD -2.33%, p=0.001) at 12 months in patients with severe obesity.