Key result
Sleeve gastrectomy and Roux-en-Y gastric bypass resulted in similar long-term BMI reductions at four years (13.23 vs 12.41 kg/m2 reduction, p=0.226).
Why the study?
Although sleeve gastrectomy and gastric bypass are effective for treating obesity and associated comorbidities, long-term results were not clearly stated in the literature.
Does sleeve gastrectomy compared to Roux-en-Y gastric bypass improve long-term BMI and comorbidities in patients with severe obesity?
Cohort (n=100)
No
Does sleeve gastrectomy compared to Roux-en-Y gastric bypass improve long-term BMI and comorbidities in patients with severe obesity?
Absolute Event Rate: 13.23% vs 12.41%
p-value: p=0.226
Both sleeve gastrectomy and Roux-en-Y gastric bypass are effective for long-term weight loss, with RYGB offering slightly better comorbidity resolution but higher minor complication rates.
Comparable long-term BMI reductions with either procedure in this cohort; extends observational data but leaves open randomized confirmation on comorbidities.
Background: Extremely obese patients can benefit greatly from bariatric surgery, a common and successful therapeutic procedure for treating obesity and accompanying medical issues. Although sleeve gastrectomy and gastric bypass have already demonstrated their effectiveness in this demographic, long-term results were not stated in the literature. The purpose of this research is to examine the long-term outcomes of sleeve gastrointestinal surgery and gastric bypass. Method: This retrospective, single-center study compares 100 patients aged 25 years and older who visited the gastrointestinal tract surgical unit at Dar El-Fouad Hospital in Cairo, Egypt, between January 1 and August 31, 2019, according to the inclusion and exclusion criteria. The patients underwent either a Roux-en-Y gastric bypass (RYGB-50%) or sleeve gastrectomy (SG-50%) for severe obesity. Follow-up occurred at one year and up to four years following surgery to collect information from the study subjects. Two tools were used to assess BMI, weight loss, complications after surgery, and incidence outcome of comorbidities after the two surgeries. Qualitative data were presented as number and percentage and frequency distribution tables, and every analysis was done at a significance value < 0.05. Result: The average age of patients within the SG group was 43.02 ± 9.19 years, whereas the average age of patients within the RYGB group was 41.02 ± 11.06 years. In addition, 74% of patients were women in both procedures. The BMI mean of the SG group was 43.90 ± 5.78, the BMI mean of the RYGB group was 42.73 ± 5.12, and the main comorbidity in both techniques was joint pain. The mean BMI at one year was 29.70 kg/m2 after SG compared with 28.64 kg/m2 after RYGB. After four years, BMI was regained within the obese range in both techniques - 30.67 kg/m2 and 30.32, respectively. Fewer postoperative complications occurred in SG than in RYGB. RYGB was superior to SG in managing dyslipidemia (DL), hypertension (HT), type 2 diabetes (T2DM), joint pain, and gastroesophageal reflux disease (GERD). Conclusion: There are no significant differences between the SG and RYGB in long-term outcomes regarding BMI before surgery and at follow-up, after four years, while there were statistically significant differences between them after four years than one year after surgery, and both groups showed a significant decrease in weight. However, RYGB shows improvement to some extent in comorbidities within follow-up period, including BMI, T2DM, HT, DL, HT, DL, GERD, and joint pain than SG, but with a higher rate of minor complications, while greater resolution of OSAS occurred in SG. Finally, at four years, there were no discernible variations in BMI between SG and RYGB because the patients' mean BMI was within the obese range once more.
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Alaidaroos et al. (2024) conducted a cohort in Severe obesity (n=100). Sleeve Gastrectomy vs. Roux-en-Y Gastric Bypass was evaluated on Reduction in BMI from baseline to 4 years (p=0.226). Sleeve gastrectomy and Roux-en-Y gastric bypass resulted in similar long-term BMI reductions at four years (13.23 vs 12.41 kg/m2 reduction, p=0.226).
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