Why the study?
Does left atrium to aorta VAD cannulation compared to left ventricular apex to aorta cannulation improve hemodynamics in a numerical cardiovascular model?
Population
Numerical models of the native cardiovascular system using the concentrated-parameter method
Comparison
Ventricular assist device support with left… vs Ventricular assist device support with left…
Design
Preclinical
Authors
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LV apex cannulation may enhance unloading at high support in models; leaves open optimal VAD cannulation site in patients.
Does left atrium to aorta VAD cannulation compared to left ventricular apex to aorta cannulation improve hemodynamics in a numerical cardiovascular model?
Numerical simulations indicate that left ventricular apex to aorta VAD cannulation is hemodynamically superior to left atrium to aorta cannulation by reducing ventricular wall tension and dilatation at high support levels.
Korakianitis et al. (2007) studied this question.
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