Key result
Chronic obstructive pulmonary disease is associated with a higher prevalence of chronic kidney disease, and the coexistence of both conditions significantly increases the risk of mortality.
Why the study?
Chronic kidney disease is often present in patients with COPD and may be underdiagnosed, leading this study to summarize recent findings on the correlation between both diseases.
Is there an association between Chronic Obstructive Pulmonary Disease and Chronic Renal Failure, and does their coexistence affect mortality?
Is there an association between Chronic Obstructive Pulmonary Disease and Chronic Renal Failure, and does their coexistence affect mortality?
The coexistence of COPD and CKD is common and associated with a higher risk of mortality, highlighting the need for improved diagnosis and management of this comorbidity.
Chronic obstructive pulmonary disease (COPD) is one of the most common diseases worldwide with its prevalence increasing with age. It is commonly comorbid with other diseases and managing patients could be difficult and expensive. Chronic kidney disease (CKD) is often present in COPD patients and may be underdiagnosed, especially if it is mild. This study intended to summarize recent findings showing the correlation between the two diseases. Studies were gathered that were published in the last 11 years, from 2010 to 2021. PubMed was used as the main source of data, but papers from the references of the included other sources were added for thoroughness. Observational studies on examining the prevalence and prognosis of comorbid COPD and CKD published in the English language were included. A higher prevalence of CKD in COPD patients was found in most studies; it was found that a higher risk of mortality is present if these diseases coexist. Further research is required and more extensive prospective studies are needed with matched control groups to support the correlation.
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Madouros et al. (2022) conducted a review in Chronic Obstructive Pulmonary Disease and Chronic Kidney Disease (n=136,066). Chronic Obstructive Pulmonary Disease vs. Patients without Chronic Obstructive Pulmonary Disease was evaluated on Prevalence of chronic kidney disease and associated mortality. Chronic obstructive pulmonary disease is associated with a higher prevalence of chronic kidney disease, and the coexistence of both conditions significantly increases the risk of mortality.
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