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The main effective method of treatment for implantation metastases remains the regional treatment strategy. Systemic chemotherapy is ineffective. The standard treatment of peritoneal carcinomatosis is cytoreductive surgery with intraperitoneal chemo-hyperthermal perfusion (HIPEC), which is performed in an open, closed or laparoscopic way. In recent years a new method of intraperitoneal chemotherapy has been developed: laparoscopic aerosol intraperitoneal chemotherapy (PIPAC). An experimental study is made to compare the efficacy and safety of various methods of intraperitoneal chemotherapy.
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Захаренко et al. (2018) studied this question.
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