Why the study?
Does aging reduce cardiac baroreflex sensitivity as measured by power spectral analysis in healthy subjects?
Population
142 healthy subjects, subdivided into five groups according to percentiles of age.
Comparison
Power spectral analysis to determine cardiac… vs Phenylephrine method (BS(phen))
Design
Cross-sectional
Authors
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Supports baroreflex sensitivity decline by middle age; leaves open whether spectral analysis supplants phenylephrine testing in practice.
Does aging reduce cardiac baroreflex sensitivity as measured by power spectral analysis in healthy subjects?
Cardiac baroreflex sensitivity declines predominantly in middle age and can be accurately assessed non-invasively using power spectral analysis.
Piccirillo et al. (2001) studied this question.
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