Why the study?
Does severe left ventricular dysfunction (LVEF ≤35%) increase the risk of sudden cardiac death early after STEMI compared to LVEF >35%?
Population
929 patients with ST elevation myocardial infarction (STEMI), mean age 55 ± 17 years.
Comparison
Severe left ventricular dysfunction (LVEF ≤35%) vs Left ventricular dysfunction >35%
Design
Cohort
Follow-up
41 ± 16 months
Authors
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LVEF ≤35% was associated with higher relative SCD risk post-STEMI but fewer absolute events; leaves open broader early risk stratification beyond LVEF.
Does severe left ventricular dysfunction (LVEF ≤35%) increase the risk of sudden cardiac death early after STEMI compared to LVEF >35%?
While the relative risk of sudden cardiac death is higher in STEMI patients with LVEF ≤35%, the absolute number of SCD events is greater in those with LVEF >35%, emphasizing the need for early risk stratification in all post-STEMI patients.
Chitnis et al. (2014) studied this question.
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