Why the study?
Giant coronary artery aneurysms are severe complications of Kawasaki disease that rarely regress, and data regarding their dynamic follow-up are scarce.
In children with Kawasaki disease, giant coronary artery aneurysms are associated with a high rate of major cardiovascular events (55.5%), although complete regression occurs in over half of patients after a mean of 2.3 years.
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Long-term giant CAA outcomes in KD remain sparsely characterized; leaves open need for prospective data to inform surveillance.
Bregel et al. (2025) studied this question.
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