Answers are grounded in this paper and cite their sources.
Adenovirus infection of monkey kidney cells in tissue culture is abortive; the early T antigens are formed efficiently and typical adenovirus cytopathic changes occur, but only limited amounts of viral structural antigens, morphologic particles, and infectious virus are produced.1-'In cells infected with SV40 virus, this block is eliminated; the viral antigens and infectivity are formed with efficiency com- parable to that in human cells.'-3This potentiation of adenovirus growth by SV40 genetic material is also observed with the adenovirus type 7 (Ad.7) strain E46+ which carries the SV40 information for production of SV40 T antigen.4-'0This report describes the application of the nucleic acid homology technique to determine whether SV40 enhancement acted at a step before or after Ad. 7 DNA synthesis, and whether SV40 DNA could.bedemonstrated in E46+.
No takes yet. Share an insight, caveat, or question.
Reich et al. (1966) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: