January 1, 1991Biochemistry

Identification of the serine residue phosphorylated by protein kinase C in vertebrate nonmuscle myosin heavy chains

View Full Paper

Ask AI

Bookmark

Population

Myosin heavy chain isolated from human platelets and chicken intestinal epithelial cells

Design

Preclinical

Authors

MCMary Anne ContiNini Hospital JSJames R. SellersHeart Failure & Transplant RARobert AdelsteinHeart Failure / Cardiomyopathy

Discussion

Member takes

Implication

Distinguishes PKC regulation of nonmuscle from smooth muscle myosin; leaves open functional and therapeutic implications.

Structured PICO

Population

Myosin heavy chain isolated from human platelets and chicken intestinal epithelial cells

Intervention

In vitro protein kinase C phosphorylation

Outcome

Identification of the phosphorylated serine residue and its amino acid sequence

Identifies the specific serine residue phosphorylated by protein kinase C in vertebrate nonmuscle myosin heavy chains, noting its absence in smooth muscle myosin heavy chains.

Cite This Study

Conti et al. (1991) studied this question.

synapsesocial.com/papers/6a7c09a10449e558d7c2c90d https://doi.org/10.1021/bi00218a012

View Full Paper

Ask AI

Bookmark

Identification of the serine residue phosphorylated by protein kinase C in vertebrate nonmuscle myosin heavy chains

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Identification of the serine residue phosphorylated by protein kinase C in vertebrate nonmuscle myosin heavy chains

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider