The ketogenic diet may precipitate life-threatening arrhythmias such as torsades de pointes in patients with underlying congenital long QT syndrome.
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Ketogenic diet may trigger TdP in congenital LQTS; hypothesis-generating case leaves open need for prospective data.
Long QT syndrome is a disorder of ventricular myocardial repolarization associated with an increased risk of life-threatening cardiac arrhythmias and sudden cardiac death. This report highlights a case of QT prolongation with torsades de pointes in a patient with baseline congenital long QT syndrome, believed to be precipitated by metabolic changes associated with the "ketogenic diet."
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Sudhakaran et al. (2019) studied this question.
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