Why the study?
QT prolongation predicts life-threatening arrhythmias, and the list of antiarrhythmic and non-cardiac drugs causing it is constantly growing and being updated.
Key points are not available for this paper at this time.
Design
Review
May support QT monitoring with high-risk drugs; leaves open need for prospective outcome trials.
QT interval prolongation is a predictor of the life-threatening cardiac arrhythmias — polymorphic ventricular tachycardia (torsade de pointes). Long QT syndrome may be congenital or acquired. It is known that a wide range of both antiarrhythmic and non-cardiac medications might lead to QT interval prolongation. List of drugs that cause QT prolongation is constantly growing and being updated. The review contains current data on the clinical significance of the control of QT interval duration within drug therapy. Clinical conditions associated with an increased risk of QT interval prolongation are described. Drugs that can induce QT prolongation are also discussed.
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Constantin Martiniuc (2021) studied this question.
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