Key result
Drugs prolonging myocardial repolarization can induce acquired long QT syndrome and potentially fatal torsade de pointes, necessitating careful prescribing to minimize risk.
Population
Patients with acquired or congenital long QT syndrome, or those exposed to QT-prolonging drugs
Design
Review
Authors
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Alerts prescribers to torsade risk with QT-prolonging drugs; confirms known associations yet leaves open individualized risk prediction.
Highlights the clinical importance of recognizing and preventing drug-induced QT prolongation and torsade de pointes.
Wilhelm Haverkamp (2001) conducted a review in QT prolongation and ventricular arrhythmias. Drugs prolonging myocardial repolarization was evaluated on Ventricular tachyarrhythmias (torsade de pointes). Drugs prolonging myocardial repolarization can induce acquired long QT syndrome and potentially fatal torsade de pointes, necessitating careful prescribing to minimize risk.
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