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February 27, 2020Molecular and Clinical OncologyOpen Access

Pulmonary metastasectomy is associated with prolonged survival among patients with bone and soft tissue sarcoma

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Why the study?

The study was conducted to evaluate the survival impact of surgical resection among patients with pulmonary metastases from bone and soft tissue sarcomas.

Does pulmonary metastasectomy improve survival in patients with pulmonary metastases from bone and soft tissue sarcomas?

Population

34 consecutive patients with ≤5 pulmonary metastases from bone and soft tissue sarcomas

Comparison

Surgical treatment vs non-surgical treatment

Design

Retrospective study

Follow-up

Median 14.5 months

Authors

JSJunya ShimizuSapporo Medical UniversityMEMakoto EmoriSapporo Medical UniversityYMYasutaka MurahashiSapporo Medical University

Discussion

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Implication

Surgical resection may extend survival in selected patients; leaves open need for prospective trials to guide practice.

Structured PICO

Does pulmonary metastasectomy improve survival in patients with pulmonary metastases from bone and soft tissue sarcomas?

P
Population
34 consecutive patients with ≤5 pulmonary metastases from bone and soft tissue sarcomas, median age 64.0 years, 19 men and 15 women.
I
Intervention
Surgical resection (pulmonary metastasectomy)
C
Comparator
Non-surgical treatment
O
Outcome
Overall survival (3- and 5-year rates)hard clinical

Pulmonary metastasectomy is associated with significantly improved 3- and 5-year overall survival in patients with ≤5 pulmonary metastases from bone and soft tissue sarcomas, regardless of age.

Cite This Study

Shimizu et al. (2020) studied this question.

synapsesocial.com/papers/6a7c11da073f483584dfb49bhttps://doi.org/10.3892/mco.2020.2009
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Five-year survival after pulmonary metastasectomy for adult soft tissue sarcoma1992 · 258 citations
  2. 2Thoracotomy for pulmonary metastatic osteosarcoma. An analysis of prognostic indicators of survival1987 · 120 citations
  3. 3Pulmonary metastasectomy for sarcoma: a systematic review of reported outcomes in the context of Thames Cancer Registry data2012 · 131 citations
  4. 4Long-term results after resection for bone sarcoma pulmonary metastases☆2009 · 64 citations
  5. 5Grading of Soft Tissue Sarcomas: Review and Update2006 · 508 citations