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March 1, 1970Circulation ResearchOpen Access

Studies on Left Atrial Automaticity in Dogs

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Population

21 open-chested dogs anesthetized with sodium pentobarbital

Design

Preclinical

Authors

MMM. MirowskiSLSun H. LauGBGustavus A. Bobb

Discussion

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Overview

This preclinical study provides foundational electrophysiological evidence that ectopic atrial activity can frequently originate in the left atrium.

Structured PICO

P
Population
21 open-chested dogs anesthetized with sodium pentobarbital
I
Intervention
Electrophysiological mapping during spontaneous rhythm, vagal stimulation, sinus node destruction, ventricular pacing, and left atrial pacing
O
Outcome
Site of origin and sequence of atrial activationsurrogate

This preclinical study provides foundational electrophysiological evidence that ectopic atrial activity can frequently originate in the left atrium.

Cite This Study

Mirowski et al. (1970) studied this question.

synapsesocial.com/papers/6a7c15b224f98b6d3fc2b29fhttps://doi.org/10.1161/01.res.26.3.317
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