Characteristics of 18F-FDG PET/CT in patients with Kimura’s disease from China

Figures

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  Fig. 1. A 79-years-old female patient admitted to hospital because of gradually swollen facial lumps with a history of lymphadenopathy for 2 years without therapy. In laboratory tests, an elevated number of eosinophils [2.53 (34.7%)] and normal IgE (6.1) were found in the peripheral blood. A On 18F-FDG PET/CT MIP (maximum intensity projection), multiple masses with FDG-avid (red arrows, SUVmax ranging from 3.0 to 6.3) were found in head-neck region, mediastinum, and abdomen. B, C On CT transverse slice (B) and 18F-FDG PET/CT transverse slice (C), these multiple masses were homogeneous density and clear boundary in bilateral parotid gland, nasal cavity, right lower eyelid (B, green arrows) with homogeneous increased FDG uptakes (C, yellow arrows). D, E On CT transverse slice (D) and 18F-FDG PET/CT transverse slice (E), there were homogeneous density and clear boundary enlarged lymph node (D, green arrows) with homogeneous increased FDG uptake (E, yellow arrows) in hepatic hilar region and retroperitoneum

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  Fig. 2. A 39-year-old male had lymphadenopathy with elevated eosinophils [3.98 (43.7)] and IgE (> 2000) in peripheral blood for half month. A On 18F-FDG PET/CT MIP, a subcutaneous mass in the left head and neck region had FDG-avid (red arrows, SUVmax = 3.5). B On CT transverse slice, there were enlarged lymph nodes of submaxillary involved submandibular gland, with homogeneous density and clear boundary. (green arrows). C On.18F-FDG PET/CT transverse slice, the increased FDG uptakes of enlarged submaxillary lymph nodes involved submandibular gland was homogeneous (yellow arrows)

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  Fig. 3. A 17-year-old male with subcutaneous mass for 6 months was histologically proven Kimura disease (KD), and oral corticosteroids irregular. He had evaluated serum eosinophil [2.63 (29.7)] and IgE (355) in laboratory tests. A On 18F-FDG PET/CT MIP, subcutaneous masses with avid FDG uptake was found in the right head and neck region (red arrows, SUVmax ranging from 3.6 to 4.1). B, C On CT transverse slice (B) and 18F-FDG PET/CT transverse slice (C), there showed incrassated right eyelid (B, green arrows) with increased FDG uptakes (C, yellow arrows). D, E On CT transverse slice (D) and 18F-FDG PET/CT transverse slice (E), a homogeneous density mass (D, green arrows) with homogeneous increased FDG uptake (E, yellow arrows) was found in the right parotid gland

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  Fig. 4. A 19-year-old male with a history of KD for 9 years after surgery found enlarged painless lymph nodes during clinical follow-up, and evaluated serum eosinophil [5.76 (46.8%)] and IgE (856). A On 18F-FDG PET/CT MIP, regional enlarged lymph node with FDG-avid (red arrows, SUVmax ranging from 2.3 to 3.6) were found in retroperitoneum and right pelvic wall. B, C On CT transverse slice (B) and 18F-FDG PET/CT transverse slice (C), there was enlarged and homogeneous density lymph nodes of retroperitoneum (B, green arrows) with homogeneous increased FDG uptakes (C, yellow arrows). (D, E) On CT transverse slice (D) and 18F-FDG PET/CT transverse slice (E), there showed homogeneous of density, but ill-defined boundary and fused enlarged lymph nodes (D, green arrows) with homogeneous increased FDG uptake (E, yellow arrows) in right pelvic wall

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  Fig. 5. The correlation between SUVmax and serum eosinophil (%) before treatment