Features of parameters of peripheral, central blood pressure and indicators of vessels rigidity in pregnant women with hypertensive disorders

Purpose. To study the parameters of peripheral and central blood pressure as well as the vascular rigidity parameters in pregnant women with physiological pregnancy and hypertensive disorders. Materials and methods. ABPM was performed using BPLab Vasotens system («Petr Telegin», Russia). The device allows to determine the propagation time of the reflected wave (RWTT), augmentation index in the brachial artery (AIx) and aorta (AIxao), arterial stiffness index (ASI), the parameters of the central blood pressure (BP). The data of 116 women in 30-39 week gestation were analyzed. The groups were: normotensive women (N), n = 42, arterial hypertension existing before pregnancy (AHBP), n = 30, gestational arterial hypertension (GAH), n = 24, and preeclampsia (PE), n = 20. Differences were considered significant at p<0.05. Results. The circadian rhythm of the central arterial blood pressure and indicators of rigidity was revealed in pregnant women regardless of normotensive or hypertensive status. The studied parameters were significantly higher in the group of pregnant women with GAH and PE compared to N and AHBP. The correlation between RWTT and AIx, AIx and AIxao was found. Conclusions. Data obtained by daily monitoring of central blood pressure and arterial stiffness can be used as additional indicators for the diagnosis of hypertension in pregnant women.