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August 12, 2026Supportive Care in CancerOpen Access

Personality traits are associated with the development and severity of chemosensory alterations during chemotherapy: a longitudinal study

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Authors

ALAngelica LippiAGAgnès GiboreauVMVéronique Mourier

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Overview

Longitudinal study shows personality traits influence sensory alterations in cancer patients, implying targeted interventions may help.

Key Points

  • This study aims to understand how personality traits affect sensory alterations during chemotherapy in cancer patients.
  • Longitudinal study involving 95 patients undergoing chemotherapy, assessed at baseline and after nine weeks.
  • Sensory alterations measured using a modified Chemotherapy-Induced Taste Alteration Scale.
  • Data analyzed using repeated-measures analyses, ANCOVA, and multivariable logistic regression models.
  • Self-reported sensory alterations prevalence increased from 24% to 60% after nine weeks.
  • Discomfort, nausea, phantogeusia/parageusia, and general taste alterations were the most reported symptoms.
  • Food neophobia was positively linked to general taste alterations, while sensitivity to reward was inversely linked to phantogeusia/parageusia and nausea.

Cite This Study

Lippi et al. (2026) studied this question.

synapsesocial.com/papers/6a7c20a306a85aed514b7882https://doi.org/10.1007/s00520-026-11074-2
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Factors Influencing Chemotherapy-Induced Taste Alterations in Cancer Patients Receiving Cisplatin Treatment: A Path Analysis2025
  2. 2A Prospective Cohort Study of the Effects of Adjuvant Breast Cancer Chemotherapy on Taste Function, Food Liking, Appetite and Associated Nutritional Outcomes2014 · 173 citations