Pulmonary Metabolism During Diving: Conditioning Blood for the Brain

During experimental diving by the awake Weddell seal, blood glucose concentration falls consistently. A large fraction of the glucose consumed from the central circulating blood appears as lactate. During diving, the lung utilizes blood lactate in preference to blood glucose as a source of both carbon and energy, and it is able to release glucose into pulmonary venous blood to supplement the supply available for brain metabolism.