March 6, 2012Journal of neurosurgery

Neurosurgical complications of direct thrombin inhibitors—catastrophic hemorrhage after mild traumatic brain injury in a patient receiving dabigatran

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Population

1 elderly patient with atrial fibrillation who presented with a rapidly expanding intracranial hemorrhage…

Design

Case_report

Authors

SGSarah T. GarberColorado Blood Cancer Institute WSWalavan SivakumarCornell University RSRichard H. SchmidtUniversity of Utah

Discussion

Member takes

Implication

May signal severe ICH risk without reversal in elderly dabigatran patients after mild TBI; leaves open need for prospective reversal studies.

Structured PICO

Population

1 elderly patient with atrial fibrillation who presented with a rapidly expanding intracranial hemorrhage after a ground-level fall

Intervention

Dabigatran

Outcome

Rapidly expanding intracranial hemorrhagesafety

This case highlights the severe risk of catastrophic hemorrhage in patients on dabigatran who suffer mild traumatic brain injury, complicated by the lack of a specific reversal agent.

Cite This Study

Garber et al. (2012) studied this question.

synapsesocial.com/papers/6a7c350862e3fa8dd03bdec7 https://doi.org/10.3171/2012.2.jns112132

Topics

Atrial fibrillation Persistent AF management Anticoagulation in AF

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Implication

May signal severe ICH risk without reversal in elderly dabigatran patients after mild TBI; leaves open need for prospective reversal studies.

Neurosurgical complications of direct thrombin inhibitors—catastrophic hemorrhage after mild traumatic brain injury in a patient receiving dabigatran

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Neurosurgical complications of direct thrombin inhibitors—catastrophic hemorrhage after mild traumatic brain injury in a patient receiving dabigatran

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider