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A heterogeneity of the Pr 1 antigen is demonstrated using dog erythrocytes: Pr 1h /Pr 1d . Pr 1h is human erythrocyte‐specific while Pr 1d is also found on dog erythrocytes. Though also the Pr 2 antigen is found on dog red cells, it is independent of Pr 1d . Pr 2 is demonstrated on dog erythrocytes also after papainization while Pr 1d is only found on untreated dog erythrocytes. The parallel of Pr 1h antigen deficiency and Pr 2 antigen increase on dog red cells in comparison with human red cells to human erythrocyte glycoproteins after periodate oxidation in comparison with untreated human red cell glycoproteins is stressed out and discussed.
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D. Roelcke (1973) studied this question.
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