Key result
Dexmedetomidine significantly reduced intraoperative bleeding scores (P=0.001) and improved surgeon satisfaction (P=0.001) compared to placebo during functional endoscopic sinus surgery.
Why the study?
Blood loss is a common concern during functional endoscopic sinus surgery, and the efficacy of dexmedetomidine on intraoperative bleeding and the surgical field required evaluation.
Does dexmedetomidine improve the quality of the surgical field and reduce intraoperative bleeding in patients undergoing functional endoscopic sinus surgery?
RCT (n=72)
Double-blind
Computer-generated
No
Does dexmedetomidine improve the quality of the surgical field and reduce intraoperative bleeding in patients undergoing functional endoscopic sinus surgery?
p-value: p=0.001
Dexmedetomidine safely and effectively improves the quality of the surgical field and reduces intraoperative bleeding during functional endoscopic sinus surgery.
Supports dexmedetomidine to reduce bleeding and raise satisfaction in FESS; confirms RCT efficacy versus placebo.
INTRODUCTION: Blood loss is a common concern during functional endoscopic sinus surgery (FESS). The present study aimed to evaluate the efficacy of dexmedetomidine (DEX) in intraoperative bleeding and surgical field in FESS. MATERIALS AND METHODS: min of the induction. The surgeon's assessment of the field during surgery and intraoperative bleeding was also recorded in this study. RESULTS: (P=0.046) min of the induction. There were no postoperative adverse effects in the DEX group. CONCLUSION: It was observed that DEX improves the quality of the surgical field and hemodynamic stability. In addition, DEX might be safely and effectively used in surgeries in which deliberate hypotension is desirable.
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Parvizi et al. (2019) conducted an RCT in Functional endoscopic sinus surgery (FESS) (n=72). Dexmedetomidine vs. Normal saline was evaluated on Intraoperative bleeding score (Boezzart's scale) (p=0.001). Dexmedetomidine significantly reduced intraoperative bleeding scores (P=0.001) and improved surgeon satisfaction (P=0.001) compared to placebo during functional endoscopic sinus surgery.
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